4. Identify reliable biomarkers for disease progression in MS with a focus on microRNAs
The word ‘
microRNAs as biomarkers for disease progression in MS
Researchers – Sebo Withoff and Jan Meilof
Project: At this moment, the onset of secondary progression in MS can only reliably be established retrospectively after a prolonged observation period. This hampers research into early treatment of disease progression. In a transversal and longitudinal study we are testing whether plasma levels of specific circulating microRNAs, small molecules involved in gene regulation, are reliable biomarkers for specific disease stages in MS.
Supported by the Dutch MS Research Foundation and Biogen