3. Develop novel
neuroimaging protocols that can monitor inflammation, demyelination, remyelination and repair.
The main focus of clinical research at the MSCNN is on improving therapeutic possibilities in progressive MS. The ultimate goal is to restore myelination and repair nerve function in MS. Current research is building the basis to achieve that goal. For instance, our work on myelin-imaging using PET-scans will ultimately result in a tool to more efficiently screen new therapies for their remyelination capacity in MS.
Investigators – Kars van der Weijden, Erik de Vries and Jan Meilof
Project: In MS, the myelin layer surrounding the axons of the nerves is damaged, which causes disruption of the nerve conduction and as a consequence the typical MS symptoms like visual problems, muscle weakness, difficulties with coordination, cognition and speech, severe fatigue, and pain. At the moment, there is no
Supported by NWO (ZonMW) and the Dutch MS Research Foundation